Genetics data
The genotyping effort of SCAPIS has been completed at the SNP&SEQ Technology Platform in Uppsala, after DNA extraction from whole blood at Karolinska Institutet Biobank.
The genotyping data holds very high quality and has been imputed using the HRC panel. If you wish to apply for genetic data, make sure to make it clear in your ethical applications that genetic analyses are planned. With this data, new avenues for research is opened up in SCAPIS, such as genome-wide association studies, genetic risk score analyses and Mendelian Randomization studies.
The available SNPs are listed in the files below. Around 700 000 SNPs for the directly genotyped data and 40 million for the imputed genotype data (around 10 to 15 million per file).
SCAPIS directly genotyped SNP list
(zip 5.7 MB)SCAPIS imputed SNP list, Chromosomes 1-5
(zip 156.3 MB)SCAPIS imputed SNP list, Chromosomes 6-12
(zip 153.1 MB)SCAPIS imputed SNP list, Chromosomes 13-22 and X
(zip 121.1 MB)
In the application form, on page 6D, you can also search for available SNPs.
See the application guidance (PDF) for details.
